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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a6952b5d8cc3d2f16dd79b3ba8c8b21e3a59111c34b895d02039d94163ae91' 
  AND token = '32ILBrE88GHiy9G8ogYfm0GnIcTgTCa3uQkBY8EPGGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}