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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145bad753a515282a057a27cdc6359435af108ac55e621f3ecdb7761e0f34fc0' 
  AND token = 'nlzopHtWOnMj2cMyfTqZDqo9mhbsWMWAv+WkI5Et3Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}