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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481b1afbe3a28e34fa735fd7a85e5d72407dbe714773f529fcd7057b0a40e6d9' 
  AND token = 'dxqzU0aJpE0ZV8kJL4PpRC0KeVc/v4ZorWQy490LGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}