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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c74f22084eb77a345ac5e2d7a3e834d0bdbcff8ac60d822e86a27e508f83bf' 
  AND token = 'DknL0t6OVDuteVSTL0vkm9OyDUUWS47GjjraE44UcEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}