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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646484aa0f8f8d212711fb41137de2e5ecae0e7b13d67805cc48acb0871ce3c2' 
  AND token = 'kuaS6P68sJUDvD/7c1g5rvPWbdZrsW1Z09jRDPrcrAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}