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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a85521156e51ea6050860ed31bc89e109737b7a83d1c5aaa62a9880e9bc6b59' 
  AND token = '5HOsh7z+kExT2mTIwZC/RdNMzLxdC7GqLsh2id9Pb/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}