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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0efd7b82d0ade774fe477bdcdc57c2beae7fee5b9db681c61e16c06aa41a64f' 
  AND token = 'CyMYIGBYlDOuWpc2LAJnUUKhdhCEn+kjCzm2c949qp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}