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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648fcb05bab9723879b4dde72a208e1cab373d13129fcbc59e51a60901bd75fc' 
  AND token = 'zdNTmza1a1DP2bxbBDpFWe2UtJTJQ/GwfC5ISbvfT+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}