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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f850841744e6ff6a150ef849610051c54897325ec4cca60392ecc2902edc52b0' 
  AND token = 'ou2PGIB4BYtBAVtJUv7+u2TkLduV9JtMOMAtbTAfnao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}