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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '026f82ab1d570fff8cd1330343594a1421f5aca18c95a2e369b76ad3c33c663b' 
  AND token = 'Biz3+7q9cDe0mRFzpfGpW6WcwUTMPpB3tiqM30wIfbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}