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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe29e88f9ea543055f2fc32b0194be4ada4c48261824c246e339c353eda9c29b' 
  AND token = 'uPg/SgYc/iBvBr4Sj1P7Z5z8CSiGNylFczp7XfxNHpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}