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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b4b7684f5c511637661dd11de3279b404c55bccb783948e9d2710542934f91' 
  AND token = 'YxOk0yLkpsOmzshDJgFz+TXPoh0xtmvf+FCi80d0o6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}