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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1371c1e0f72ef26b0e51aee4d81378d2448506c3e1f5575a35ba0f62bc5a7f4b' 
  AND token = 'V6v0NE6FF1dEDDRfb5bGpFPavFTqBmrOVLabEl3Oflo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}