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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf36c3c114552f8075d0420448eeba849821b9dc508e7b2d49147304d963aaa2' 
  AND token = 'hsHm3z0mj6bHxKxmx5C5DlNvMA/f0wfFSSjtLc/hbE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}