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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc46d80864c38285b07b2ce7e44de357727debc22d6658ebcca9c4f4ee308259' 
  AND token = '5o/DpmHEWtJ06n+3NwTngkLFJFCjCZlps+rLOPbLLXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}