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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04cd705365a8fa81e8ae387921220e84e829698a7cb855354e4d1a1735018729' 
  AND token = 'NcUSG5RgYEaAs+7prcDsRgL5HI61bdLYpiihYprzwvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}