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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca07e1d5946e3ac8cdc2b9aaafc5f095293f9117ee76ff2c05815a791e29843' 
  AND token = 'O6is2nU7vNlzyzJPCsOf3+9yAKO8oeYd1kX/FhcVhuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}