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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bfc9d25d820f2fc0dfd13f8f713036c7cfd43bcc633b78e2ae22204c2d8ddc' 
  AND token = '2rVVJQ3ixRY0jHDtgVXuSBlnCt9l6VPFa3oDtiAI80U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}