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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfd0055649ebe647d7322f2867b6558a4301bb8d04f6eaf8a77ae0101c2c4249' 
  AND token = 'u20Nsg8lFdzqxmYw8K1t+8sewKwdyxsF8cZo5Mf5huo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}