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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc05cbe6de0f6bd5f9acce9992b52d118f3f31b1f601bb2aa1b30c3100c8660' 
  AND token = 'COqXRS67+uLgcfBY9Rr4xBpoTlTzDS36J0ugA6ytUr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}