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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f0a0a0985e29912909a8470ed5d48eb61c3304d0e18b6afc8133f3e5320254' 
  AND token = 'b9ERdUy0KODQJ3vb8Qad5fbYLK5dI/b8Y5UEZCtNU+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}