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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9211ec8385878735d2c8ca193797dc65abba5ef27184d1c11559bf0b1141702f' 
  AND token = 'Zr9iYF8qOErrcj1NYGPvLzbg9P0GGxHw/ZfdjNQ52mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}