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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b5e133f87e54d00ab452645d05db258d38c0d640993dba5060eedb383cd7a2' 
  AND token = 'h9KmyOqZfI7NgOLXHRcGbG3Le9+QqWKGySzo1vB4TQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}