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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f443824267e8b76cb5b6f936b4c3130934dcf2303d9787c07e78fc7a8e5f9619' 
  AND token = 'z+91FZWD5Yqo3LosvfxqsaPMg1e67rqdiZC2IIgyQMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}