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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51357e3aa05a801552b03a9464f2e683b5862c99d1d21d763ce7a00f224a513e' 
  AND token = 'n133m9zcSKV7suHBZxoIhMSXZvIE6u8WhlpwH5BP8Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}