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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24ad9533761d65b308f58c4a6ed72aa92946e3b6648719de4f25e3980733894' 
  AND token = 'rutwT0IFjL7OIsaOEGLUcxLxgaTdQjh/SVsnRY1csto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}