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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b2b6328a61f5377f7b10acd67d341a2e0c492b64259be72dd5d9c768aa2e35' 
  AND token = 'E4t4Ot4YOoJYMUDCoHgqUmx4ZJB8t54cqemMRiijtu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}