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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad24de3b43e9e17fe092cdb3b10a261e1d921248628242b9c2db5db06194c02' 
  AND token = 'NmRWsedoTmiK0jbrhOonR++Wk/4lxjt1aSOQBABl5Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}