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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a28965ff654780f0a53243cae8fda53705b63f048c17cc630d7c26126c56d6' 
  AND token = 'A0V1VBu3BT3qoJS8DMd1w6S5ktTQXGsbF8H6uerhoZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}