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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1330c094388ebecd9b534c70e632410a2dec9891e48838aaf4f156d6af3d433a' 
  AND token = 'r8oPznTfd+5pBGVDuugE6Rnv2ucgZ2yGIHW2rFqrju8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}