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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1cf82f3b82630f242380451a61f4eb0e5bf019c82aded511fccdec673ab8006' 
  AND token = 'a9pb78xJtmE3Yzf84VPAvfz6cYfuJ1U4qrb0XuvK0wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}