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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1bb6a625366ae77bdd9564a4abf21eff38ad73f223b7bf0e48b2f19957b6766' 
  AND token = 'GTq/j0ddWW+QNj0Lw/HtDLi0I6ZDLAZjaujfDci4Aao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}