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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e0f8e49ab164b5478addb18f515c5f298d5c0eaab854802405fd0d6bc46cbf' 
  AND token = 'voEx7zXGsIFpM7Z81FaZa3FqIQjmCu8XIfm6V2rMUJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}