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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '766a42f67ac3584e5bd4ac9f07eca0b3a0d175445647f703467b0c93286c314e' 
  AND token = 'CKk44Zd+gSWlmUtGDhNOIaQToF4x50fOVBtSyU6KXbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}