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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b3f2a1b8ad6ce605e1f4c8cfbb273a3a93f54bb099207f1f8aa7f3cbc829279' 
  AND token = 'YnKHZ9QRTspTMc5Eg9/kL7NKT6HEJqpH2KidvW1BTlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}