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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2075609419f286df2708862d1f1cfebad0b896c9fc762fbc7453c2beb6a09e76' 
  AND token = 'y1YgXeSgIGIYERLIMNxlgrDhagGhU6h19Ct2W5LDExY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}