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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645befc0202dad3d42fbf8fe9303235891efd728225076440a63e81803d9c8a4' 
  AND token = 'XsO9KBaPlSKL5jsqK1BOUmoGPI1E2f6USIckVJiJeiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}