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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d75e3cb4b0198b26a85519b7bcf01a9fb94a52301c1e67649b965eff88aeae4' 
  AND token = 'L8Be/40rN0cGgh6qPlOXwV1e6Hh2tJ99JS4xeCtZfHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}