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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b7bc0cd752834fc99f1d41beceddbd3a0136d70fd8d00af2b08dfb3bad3025' 
  AND token = 'ZDsHkcZo0I+rYmm6YpxHALK4Cy2BGbIQvcMWTO0d7iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}