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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44e35f505e432cc5ca1ca74940a0dccc80cb45df91b3e362432752bc8b4af89' 
  AND token = 'UVw+UKt0RGmHj/NbSQ+CTk9iq/LBf+cQLD2oiZyKTa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}