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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b499d67f59d54f1e42f43c0b1fa613a4b4f536d95118fc945e6d63aa54db8ebc' 
  AND token = 'UK01YR47bGvVD6ZeOYBAGnNAThyvq04lj0T9DilyFC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}