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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6eacc1c0d9867ab2c2968663661fe3278d72f9c928d6c5e7dd0259b1cba423' 
  AND token = 'UOiZbvk94mXYWQYwRL9KADMwsv7aevgfK1f1cQk83RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}