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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25fb88b001e3388ea867eac33e763c10345fc22740b50dd08badc42f71d7ac31' 
  AND token = 'QikY1Fdg8CbU+iOLly3qw+DZ92ZG3FHQBphtFdBBJGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}