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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01af7302b70158c6f446500222a54fb7b6c9a01f3aa3f84f7fbd71ed85f59bc0' 
  AND token = 'DmWADTlSRO6lle2jvndKBnBg5uduOmOzzpWLzTas+XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}