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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8030499f1929bee7c7e99efeba616cebe21da7aaf0114740c81969398363d8f' 
  AND token = 'CS/zMGIHbCt/hDRU6JtYwtXFHlB822I7KfLHcAd9Xmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}