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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e862660b9e7817b1a9cc5ae7f0887edd799c21ba5a19e5b75bf5a594aa32f50f' 
  AND token = '0x8F0FaUfGEt+8ONZ8i7T1GgzU1ed0Om1GFMiYo4rv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}