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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535a53f77f19ac1057a3fef94fe190f00bf9f56dc9a639e16f4f3f4a281e4331' 
  AND token = 'paxKKJDfP/f/btsaZpEwshd9lcImPbaw/ABQF9wAE3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}