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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b334032430efd42f0a17ad0471497220e5ba6cf192dd689eb8cde6a2aeaf28a' 
  AND token = 'TMPQJcpU+Hw+W+Yf1u0XsVRvr9/yxiRrzlje0s6D3BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}