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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b3f7b2b1b13d1e0b42c99652763798f9348b5497611b2d197888b654a1fb96' 
  AND token = 'NeIiGG9rYfj6+ux8NHT+MtiINUe0FR9bPe7LxhDW7ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}