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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755a15fd4856155642c53d698a12c79d571654e84e912b3b10d862e1615c44ea' 
  AND token = 'pZWCfWGkav/SDIDbG3u7QahsPINS7yuIw8/ZEsusbOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}